ABCB11

ABCB11
Identifiers
Aliases	ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP, ATP binding cassette subfamily B member 11
External IDs	OMIM: 603201; MGI: 1351619; HomoloGene: 74509; GeneCards: ABCB11; OMA:ABCB11 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	169,031,324 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	69,172,960 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; testicle; ; mucosa of transverse colon; ; left testis; ; subcutaneous adipose tissue; ; right testis; ; olfactory zone of nasal mucosa; ; islet of Langerhans; ; gonad; ; ventricular zone;
	Top expressed in
	left lobe of liver; ; epithelium of small intestine; ; sexually immature organism; ; yolk sac; ; lumbar subsegment of spinal cord; ; spermatid; ; migratory enteric neural crest cell; ; esophagus; ; stomach; ; medial head of gastrocnemius muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	ATPase-coupled transmembrane transporter activity; nucleotide binding; ABC-type bile acid transporter activity; transporter activity; canalicular bile acid transmembrane transporter activity; ATPase activity; P-type sodium transporter activity; ATP binding;
Cellular component	integral component of membrane; plasma membrane; apical part of cell; integral component of plasma membrane; intercellular canaliculus; extracellular exosome; membrane;
Biological process	canalicular bile acid transport; transmembrane transport; bile acid biosynthetic process; sodium ion transmembrane transport; bile acid and bile salt transport; transport;
	Sources:Amigo / QuickGO
Orthologs
	8647
	27413
	ENSG00000276582; ENSG00000073734
	ENSMUSG00000027048
	O95342
	Q9QY30
	NM_003742
	NM_021022; NM_001363492
	NP_003733
	NP_066302; NP_001350421
	Wikidata
View/Edit Human	View/Edit Mouse

ATP-binding cassette, sub-family B member 11 (ABCB11), also known as the bile salt export pump (BSEP), is a protein which in humans is encoded by the ABCB11 gene.