5-Chloro-DMT
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| Other names | 5-Chloro-N,N-dimethyltryptamine; 5-Chloro-DMT; 5-Cl-DMT |
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| Formula | C12H15ClN2 |
| Molar mass | 222.72 g·mol−1 |
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5-Chloro-N,N-dimethyltryptamine (5-chloro-DMT or 5-Cl-DMT) is a tryptamine derivative related to compounds such as 5-bromo-DMT and 5-fluoro-DMT. It acts as a serotonin receptor agonist and has primarily sedative effects in animal studies. It is known to have affinity for and to act as an agonist of the serotonin 5-HT1A, 5-HT2A, and 5-HT2C receptors. It produces the head-twitch response, a behavioral proxy of psychedelic effects, in rodents. The compound has been sold as a designer drug.