5-Chloro-DMT

5-Chloro-DMT
Clinical data
Other names5-Chloro-N,N-dimethyltryptamine; 5-Chloro-DMT; 5-Cl-DMT
Identifiers
  • 2-(5-chloro-1H-indol-3-yl)-N,N-dimethylethanamine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC12H15ClN2
Molar mass222.72 g·mol−1
3D model (JSmol)
  • CN(C)CCC1=CNC2=C1C=C(C=C2)Cl
  • InChI=1S/C12H15ClN2/c1-15(2)6-5-9-8-14-12-4-3-10(13)7-11(9)12/h3-4,7-8,14H,5-6H2,1-2H3
  • Key:BXYDWQABVPBLBU-UHFFFAOYSA-N

5-Chloro-N,N-dimethyltryptamine (5-chloro-DMT or 5-Cl-DMT) is a tryptamine derivative related to compounds such as 5-bromo-DMT and 5-fluoro-DMT. It acts as a serotonin receptor agonist and has primarily sedative effects in animal studies. It is known to have affinity for and to act as an agonist of the serotonin 5-HT1A, 5-HT2A, and 5-HT2C receptors. It produces the head-twitch response, a behavioral proxy of psychedelic effects, in rodents. The compound has been sold as a designer drug.