2025 Santa Cruz Challenger
| 2025 Santa Cruz Challenger | |
|---|---|
| Date | 16–21 June |
| Edition | 6th |
| Surface | Clay |
| Location | Santa Cruz de la Sierra, Bolivia |
| 2024 Champions | |
| Singles | |
| Juan Manuel Cerúndolo | |
| Doubles | |
| Hady Habib / Trey Hilderbrand | |
The 2025 Santa Cruz Challenger was a professional tennis tournament played on clay courts. It was the sixth edition of the tournament which was part of the 2025 ATP Challenger Tour. It took place in Santa Cruz de la Sierra, Bolivia between 16 and 21 June 2025.