2025 Copa Colsanitas – Singles
| Singles | |
|---|---|
| 2025 Copa Colsanitas | |
| Champion | Camila Osorio |
| Runner-up | Katarzyna Kawa |
| Score | 6–3, 6–3 |
| Draw | 32 |
| Seeds | 8 |
Defending champion Camila Osorio defeated Katarzyna Kawa in the final, 6–3, 6–3 to win the singles tennis title at the 2025 Copa Colsanitas. Osorio was the second player, after countrywoman Fabiola Zuluaga, to win three titles at the tournament. She saved a match point en route to the title, in the second round against Emina Bektas.
Aged 16 years and 1 month old, Julieta Pareja was the youngest player to reach a WTA Tour semifinal since Coco Gauff at the 2019 Upper Austria Ladies Linz Open.