2024 Miami Open – Women's singles

Danielle Collins defeated Elena Rybakina in the final, 7–5, 6–3 to win the women's singles tennis title at the 2024 Miami Open. It was her first WTA 1000 title, and her third WTA Tour title overall. Collins was the second unseeded woman to win the tournament, after Kim Clijsters in 2005. Ranked as the world No. 53, Collins was the lowest-ranked women's singles champion in the tournament's history, and the oldest first-time WTA 1000 champion since Elena Vesnina at the 2017 Indian Wells Open.

Petra Kvitová was the reigning champion, but did not participate due to pregnancy. This was the third consecutive year that the reigning champion did not defend the title, following Ashleigh Barty's withdrawal just before her professional retirement in 2022, and Iga Świątek withdrawal due to injury in 2023.

Rybakina became the first woman to reach consecutive Miami Open finals since Serena Williams from 2013 to 2015.

This tournament marked the return to professional tennis of former world No. 1 Simona Halep. She lost to Paula Badosa in the first round. This was her first appearance since the 2022 US Open, following a suspension due to a doping violation.

This tournament marked the final professional appearance of Canadian Open champion Camila Giorgi, who later announced her retirement. She lost to Świątek in the second round.