2023 US Open – Women's singles

Coco Gauff defeated Aryna Sabalenka in the final, 2–6, 6–3, 6–2 to win the women's singles tennis title at the 2023 US Open. It was her first major singles title. Gauff was the first American teenager to win the title since Serena Williams in 1999, and one of three teenagers to win the title within five years (following Bianca Andreescu in 2019 and Emma Raducanu in 2021). Sabalenka was the first woman since Williams in 2016 to reach at least the semifinals of all four majors in a season.

Iga Świątek was the defending champion, but lost to Jeļena Ostapenko in the fourth round. Her defeat guaranteed a first-time US Open champion. As a result of Świątek's fourth-round defeat, Sabalenka claimed the world No. 1 singles ranking for the first time in her career.

The third-round match between Caroline Wozniacki, ranked No. 623, and Jennifer Brady, ranked No. 433 (both playing their first majors in over two years), was the first third-round match in any major between two players outside the top 300 in singles rankings, male or female. This was the first major since the 2019 US Open in which all eight quarterfinalists were seeded.