2022 Zavarovalnica Sava Portorož – Singles
| Singles | |
|---|---|
| 2022 Zavarovalnica Sava Portorož | |
| Champion | Kateřina Siniaková |
| Runner-up | Elena Rybakina |
| Score | 6–7(4–7), 7–6(7–5), 6–4 |
| Draw | 32 |
| Seeds | 8 |
Kateřina Siniaková defeated Elena Rybakina in the final, 6–7(4–7), 7–6(7–5), 6–4 to win the singles tennis title at the 2022 WTA Slovenia Open. It was her first singles title since 2017.
Jasmine Paolini was the defending champion, but lost to Siniaková in the quarterfinals.