2022 Open 13 Provence – Singles
| Singles | |
|---|---|
| 2022 Open 13 Provence | |
| Champion | Andrey Rublev |
| Runner-up | Félix Auger-Aliassime |
| Score | 7–5, 7–6(7–4) |
| Draw | 28 (4 Q / 3 WC ) |
| Seeds | 8 |
Andrey Rublev defeated Félix Auger-Aliassime in the final, 7–5, 7–6(7–4) to win the singles title at the 2022 Open 13 Provence.
Daniil Medvedev was the defending champion, but chose not to defend his title.