2022 Australian Open – Wheelchair quad singles
| Wheelchair quad singles | |
|---|---|
| 2022 Australian Open | |
| Champion | Sam Schröder |
| Runner-up | Dylan Alcott |
| Score | 7–5, 6–0 |
Sam Schröder defeated the seven-time defending champion Dylan Alcott in the final, 7–5, 6–0 to win the quad singles wheelchair tennis title at the 2022 Australian Open. It marked Alcott's final professional appearance. The final was played in the Rod Laver Arena.