2021 Primera B de Chile
| Season | 2021 |
|---|---|
| Dates | 3 April – 10 December 2021 |
| Champions | Coquimbo Unido (4th title) |
| Promoted | Coquimbo Unido |
| Relegated | San Marcos de Arica |
| Matches played | 246 |
| Goals scored | 602 (2.45 per match) |
| Top goalscorer | Manuel López (21 goals) |
| Biggest home win | Dep. Copiapó 5–0 Rangers (12 September) Dep. Iquique 6–1 Dep. Santa Cruz (3 October) |
| Biggest away win | Dep. Santa Cruz 1–7 Coquimbo (18 May) |
| Highest scoring | Dep. Santa Cruz 1–7 Coquimbo (18 May) |
← 2020 2022 → | |
The 2021 Primera B de Chile, also known as Campeonato Ascenso Betsson 2021 for sponsorship purposes, was the 67th season of the Primera B de Chile, Chile's second-tier football league. The season started on 3 April 2021.
Coquimbo Unido were the champions, winning their fourth title in the competition as well as clinching promotion to Primera División with a 2–1 victory over Fernandez Vial on 13 November, the last matchday of the regular season.