2021 Paraguayan Primera División season
| Season | 2021 |
|---|---|
| Dates | 5 February – 5 December 2021 |
| Champions | Apertura: Libertad (21st title) Clausura: Cerro Porteño (34th title) |
| Relegated | Sportivo Luqueño River Plate |
| Copa Libertadores | Cerro Porteño Libertad Guaraní Olimpia |
| Copa Sudamericana | Nacional Guaireña Sol de América (via Copa Paraguay) |
| Matches played | 180 |
| Goals scored | 456 (2.53 per match) |
| Top goalscorer | Apertura: Leonardo Villagra (10 goals) Clausura: Sebastián Ferreira and Lorenzo Melgarejo (9 goals each) |
| Biggest home win | Libertad 5–0 Sportivo Luqueño (29 August) Libertad 5–0 River Plate (3 December) |
| Biggest away win | 12 de Octubre 0–5 Sol de América (20 February) Guaraní 1–6 Libertad (16 May) |
| Highest scoring | Guaraní 1–6 Libertad (16 May) |
← 2020 2022 → | |
The 2021 División Profesional season (officially the Copa de Primera TIGO-Visión Banco 2021 for sponsorship reasons) was the 87th season of the Paraguayan Primera División, the top-flight professional football league in Paraguay. The season began on 5 February and ended on 5 December 2021. The fixtures for the season were announced on 15 January 2021. Olimpia were the defending champions after winning the 2020 Clausura tournament.
In the Torneo Apertura, Libertad secured their twenty-first league title with one match to spare following Nacional's loss to River Plate on 23 May, whilst in the Torneo Clausura Cerro Porteño won their thirty-fourth league title after drawing with eventual runners-up Guaraní 2–2 on the last matchday played on 4 December.