2019 Italian Open – Women's singles
| Women's singles | |
|---|---|
| 2019 Italian Open | |
| Champion | Karolína Plíšková |
| Runner-up | Johanna Konta |
| Score | 6–3, 6–4 |
| Draw | 56 (8 Q / 5 WC ) |
| Seeds | 16 |
Karolína Plíšková defeated Johanna Konta in the final, 6–3, 6–4 to win the women's singles tennis title at the 2019 Italian Open.
Elina Svitolina was the two-time defending champion, but lost in the second round to Victoria Azarenka.
Naomi Osaka and Simona Halep were in contention for the WTA no. 1 singles ranking at the beginning of the tournament. Osaka retained the top ranking following Halep's loss in the second round.
This was the first Italian Open in 8 years which was not won by neither of Maria Sharapova, Serena Williams or Svitolina.