2018 Karshi Challenger – Singles
| Singles | |
|---|---|
| 2018 Karshi Challenger | |
| Champion | Egor Gerasimov |
| Runner-up | Sergey Betov |
| Score | 7–6(7–3), 2–0 ret. |
Egor Gerasimov was the defending champion and successfully defended his title.
Gerasimov won the title after Sergey Betov retired trailing 6–7(3–7), 0–2 in the final.