2013 Western & Southern Open – Men's singles
| Men's singles | |
|---|---|
| 2013 Western & Southern Open | |
| Champion | Rafael Nadal |
| Runner-up | John Isner |
| Score | 7–6(10–8), 7–6(7–3) |
Rafael Nadal defeated John Isner in the final, 7–6(10–8), 7–6(7–3) to win the men's singles tennis title at the 2013 Cincinnati Open. It was his record-extending 26th Masters title.
Roger Federer was the defending champion, but lost in the quarterfinals to Nadal.