2010 Sony Ericsson Open – Men's singles

Men's singles
2010 Sony Ericsson Open
Champion Andy Roddick
Runner-up Tomáš Berdych
Score7–5, 6–4
Draw96 (12Q / 4WC)
Seeds32

Andy Roddick defeated Tomáš Berdych in the final, 7–5, 6–4 to win the men's singles tennis title at the 2010 Miami Open. It was his first Masters title since 2006, and his second career Miami Open title.

Andy Murray was the defending champion, but lost to Mardy Fish in the second round.

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