2010 Serbia Open – Singles

Singles
2010 Serbia Open
Champion Sam Querrey
Runner-up John Isner
Score3–6, 7–6(7–4), 6–4

Sam Querrey defeated John Isner in the final, 3–6, 7–6(7–4), 6–4 to win the singles tennis title at the 2010 Serbia Open.

Novak Djokovic was the defending champion, but retired in the quarterfinals against Filip Krajinović.