2004 NASDAQ-100 Open – Women's singles
| Women's singles | |
|---|---|
| 2004 NASDAQ-100 Open | |
| Champion | Serena Williams |
| Runner-up | Elena Dementieva |
| Score | 6–1, 6–1 |
| Draw | 96 (9WC/12Q/2LL/6PR) |
| Seeds | 32 |
Two-time defending champion Serena Williams defeated Elena Dementieva in the final, 6–1, 6–1 to win the women's singles tennis title at the 2004 Miami Open.
This tournament marked the first career meeting between Serena Williams and Maria Sharapova; Williams won in straight sets in their fourth-round encounter.