2001 US Open – Women's singles
| Women's singles | |
|---|---|
| 2001 US Open | |
| Champion | Venus Williams |
| Runner-up | Serena Williams |
| Score | 6–2, 6–4 |
| Draw | 128 |
| Seeds | 32 |
Defending champion Venus Williams defeated her sister Serena Williams in the final, 6–2, 6–4 to win the women's singles tennis title at the 2001 US Open. It was her fourth major singles title. Venus did not lose a set during the tournament. The championship match was the first of nine major finals contested by the Williams sisters, and the first US Open women's singles final to take place during American television prime time.