2000–01 Cypriot First Division
| Season | 2000–01 |
|---|---|
| Champions | Omonia (18th title) |
| Relegated | Nea Salamina Digenis Aris |
| Champions League | Omonia (2nd qualifying round) |
| UEFA Cup | Olympiakos (qualifying round) Apollon (qualifying round; via Cypriot Cup) |
| Intertoto Cup | Anorthosis (1st round) |
| Matches played | 182 |
| Goals scored | 646 (3.55 per match) |
| Top goalscorer | Rainer Rauffmann (30 goals) |
2001–02 → | |
The 2000–01 Cypriot First Division was the 62nd season of the Cypriot top-level football league. Omonia won their 18th title.