2,5-Dimethoxy-4-(2-fluoroethyl)amphetamine

DOEF
Clinical data
Other namesDOEF; 2,5-Dimethoxy-4-(2-fluoroethyl)amphetamine; 4-(2-Fluoroethyl)-2,5-dimethoxyamphetamine
Identifiers
  • 1-[4-(2-fluoroethyl)-2,5-dimethoxyphenyl]propan-2-amine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC13H20FNO2
Molar mass241.306 g·mol−1
3D model (JSmol)
  • C1(=CC(=C(C=C1CC(C)N)OC)CCF)OC
  • InChI=1S/C13H20FNO2/c1-9(15)6-11-8-12(16-2)10(4-5-14)7-13(11)17-3/h7-9H,4-6,15H2,1-3H3 Y
  • Key:QLENKWFQUHHBKZ-UHFFFAOYSA-N Y
 NY (what is this?)  (verify)

2,5-Dimethoxy-4-(2-fluoroethyl)amphetamine (DOEF) is a lesser-known psychedelic drug and member of the DOx family. DOEF was first synthesized by Alexander Shulgin. In his book PiHKAL, the dosage range is listed as 2 to 3.5 mg, and the duration is listed as 12 to 16 hours. Very little data exists about the pharmacological properties, metabolism, and toxicity of DOEF.