1980–81 Yugoslav Second League
| Season | 1980–81 |
|---|---|
| Champions | Osijek (West Division) Teteks (East Division) |
| Promoted | Osijek Teteks |
| Relegated | Maribor Vrbas Bosna Radnički Pirot Lovćen Rabotnički Vlaznimi Đakovica |
← 1979–80 1981–82 → | |
The 1980–81 Yugoslav Second League season was the 35th season of the Second Federal League (Serbo-Croatian: Druga savezna liga), the second level association football competition of SFR Yugoslavia, since its establishment in 1946. The league was contested in two regional groups (West Division and East Division), with 16 clubs each.