1921 APFA season

1921 NFL season
Regular season
DurationSeptember 25 – December 18, 1921
ChampionsChicago Staleys
Pros
All-Americans
Bulldogs
Cardinals
Staleys
Indians
Panhandles
Triangles
Tigers
Crimson Giants
Packers
Flyers
Brecks
Marines
Brickley Giants
Jeffersons
Independents
Senators
Traveling teams
Celts
Pros
Kardex
APFA teams

The 1921 APFA season was the second season of the American Professional Football Association, which was renamed the National Football League in 1922.

The Staleys, who moved their base of operations from Decatur, Illinois, to Chicago mid-season, were named the APFA Champions over the Buffalo All-Americans.